If you're a Cheez Whiz purist, by all means, substitute it in and go for it.
You can really use any cut of venison for this. I usually go with a roast from the back legs, as those cuts have great muscle definition and are ideal for slicing. I typically save my backstraps for steaks, but again, use what you have. You can’t go wrong — whether it’s backstrap, top or bottom round, flank, or even neck meat.
Just make sure to trim off any silver skin, excess fat or sinew. Also, pop the venison in the freezer for about 30 minutes before slicing; it firms up the meat and makes it much easier to cut thin. Trust me.
This meal is best served alongside good friends with football on the TV or while swapping hunting stories.

1. Prepare the venison
Freeze the venison for 30–45 minutes to make it easier to slice.
Slice thinly across the grain and set aside.
2. Cook the vegetables
Heat a large skillet or griddle over medium-high heat.
Add olive oil or butter.
Sauté onions and peppers until softened and slightly caramelized, about 6-8 minutes.
Remove and set aside.
3. Cook the venison
In the same pan, add venison slices in a single layer.
Season with salt, pepper and optional seasoning rub.
Cook quickly—1-2 minutes per side—until just browned. (Venison cooks fast, so don’t overdo it.)
Add Worcestershire sauce, if using.
4. Combine and melt the cheese
Return the peppers and onions to the pan and mix with the venison.
Shape into sandwich-sized piles.
Top each pile with provolone slices.
Cover with a lid and let the cheese melt, about 1-2 minutes.
5. Build the sandwiches
Toast hoagie rolls lightly, if desired.
Using a spatula, scoop the cheesy venison mixture into each roll.